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Epub 2017 Jan 24

Vanin-1 licenses inflammatory mediator production by gut epithelial cells and controls colitis by antagonizing peroxisome proliferator-activated receptor activity

Both experimental (animals) and clinical studies have shown that many hormones can induce IR including glucocorticoids (GCs), 97 cortisol, 98 growth hormone, 99 and human placental lactogen, 100 which may decrease the insulin-suppressive effects on glucose production and reduce the insulin-stimulated glucose uptake