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Description

M.KundertJ

[PubMed: 15161945] (Among 107 patients with atrial fibrillation or flutter treated with dofetilide in clinical practice, none developed torsades de pointes although 26% had excessive QTc prolongation, and rates of conversion to and maintenance of normal sinus rhythm were similar or higher than reported in registration trials

NIH Public Access 24 (1), 7379

The formation of NFT in an aerobic intracellular environment raises the question of its stability and its interaction with biological molecules such as the omnipresent glutathione