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* Route If it is the first exposure, is it by a route that may sensitize people, usually via inhalation or skin contact, or by ingestion, which is much less likely to do so

Am J Respir Crit Care Med 162 : 23412351 Miller MR, Hankinson J, Brusasco V, Burgos F, Casaburi R, Coates A, Crapo R, Enright P, van der Grinten CP, Gustafsson P, Jensen R, Johnson DC, MacIntyre N, McKay R, Navajas D, Pedersen OF, Pellegrino R, Viegi G, Wanger J 2005 Standardisation of spirometry

Treating LMNA (R453W) fish with creatine may help reduce muscle damage caused by laminopathy and provide additional energy for skeletal muscle

Thus it can be seen as arginine plays a crucial role in stability and flexibility of protein, as this types of interaction can be elucidated by opposite charge attraction, length and flexibility of side chain, and the potential to produce excellent hydrogen-bonding geometries with other biomolecules like nucleobases and phosphate groups