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thus, we need to pay more attention when using this as it can impact humans and related ecosystems [194, 195]

A limitation of this study is that all CLN3 patientderived replicates originate from a single individual

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In vivo assessments demonstrated that AANLCs significantly reduced tumor volume (3.30 0.23 cm 3 ) and weight (5.37 0.41 g), enhanced cytotoxicity (92.36%), and improved survival outcomes (49.66 days), compared to the free drug administered as suspension (0.25%w/v Na-CMC) (42 days)