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The peptideMPO complex showing the strongest binding affinity from molecular docking (see section 2.4.1) was selected for simulation using GROMACS2022

Historically, hydroquinone (HQ) 4% as monotherapy, but also in combination with tretinoin and topical steroids (triple cream), has been an established topical, first-line treatment over years, but concerns about its side effects (permanent depigmentation, ochronosis, potential risk of cancer due to its metabolites) have prompted the use of potentially safer alternatives and the withdrawal of HQ in many countries

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Store unopened and opened vials at controlled room temperature, 20C25C (68F77F), away from direct light and temperature extremes