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to date, no clear evidence has been found that it directly induces ROS production, and the amplification effect of related inflammatory damage may need to be mediated through other downstream pathways (114)

B vitamins are coenzymes needed for energy production, proper nerve function, normal vision and skin health, digestive system health, protein metabolism, carbohydrate metabolism, red blood cell formation, DNA and RNA synthesis, fatty acid synthesis, amino acid synthesis and the manufacture of sex and stress related hormones

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61 The combination of EGFR inhibitor with cisplatin-radiation requires further preclinical investigation