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Attention should be focused on indicators such as methionine and S-adenosylmethionine in plasma and methyl tetrahydrofolate in CSF [93, 95]

If you have numbness, tingling, balance problems, or memory changes, see a clinician promptly, because neurological damage from vitamin B12 deficiency can become permanent when treatment is delayed

These include: covering the ulcer with a paste made from baking soda using other topical pastes placing milk of magnesia on the ulcer using a mouth rinse made from salt water and baking soda using a mouth rinse that contains a steroid to reduce pain and swelling applying ice to the ulcer placing a damp tea bag on the ulcer taking supplements if you have deficiencies in certain nutrients, including vitamin B9 (folate), vitamin B12, zinc, and iron using over-the-counter topical products that are made with benzocaine, like Orajel and Anbesol trying natural remedies, such as echinacea, myrrh, and licorice root (may come in various forms, like teas or oils) You can take these steps to help reduce the occurrence of mouth ulcers: Avoid foods that irritate your mouth