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Description

The successfully ligated construct was validated via restriction digestion, as well as DNA sequencing through the Duke Life Science Facility with a V2 forward primer (5 AGCAGAGCTCGTTTAGTGAACC 3)

An effect of FLNA in regulating SSTR2 internalization rate was also reported ( Furthermore, in vitro experiments in tumoral somatotrophs demonstrated that FLNA is required for SSTR2-induced reduction of cyclin D1 and caspase3/7 activation, suggesting a crucial role for FLNA in mediating antiproliferative and proapoptotic effects of SSTR2