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Tissue damage in the amyloidoses: Transthyretin monomers and nonnative oligomers are the major cytotoxic species in tissue culture

*Correspondence: Lena Palaniyappan [email protected] This article was submitted to Neuroimaging and Stimulation, a section of the journal Frontiers in Psychiatry Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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These interventions could be alterations in lifestyle [105], modulating SASP, probiotics, antioxidants, inhibitors of NF-B and mTOR, and activators of Nrf2, sirtuins, and AMPK, as well as senolytic drugs