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p=0.984), and showed no significant differences depending on smoking duration, smoking intensity, and cumulative dose of smoking (Table 4)

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First, each possible target for Rg1 could be determined by using the SwissTargetPrediction tool (Our study used SwissTargetPrediction ( Next, genes related to PD could be filtered using the GeneCards database ( These targets were then imported into Cytoscape 3.10 to establish a drug-target-disease network, followed by the construction of a protein-protein interaction (PPI) network using String database ( The PPI network was useful for the selection of targets for further analysis, representing areas with established experimental support