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By degrading damaged organelles and clearing intracellular harmful substances, autophagy helps maintain cellular homeostasis and can influence the apoptotic process to some extent

For example, platinum (IV) prodrugs activated by intracellular GSH have demonstrated enhanced tumor selectivity and reduced systemic toxicity in clinical trials

At the University of California, Santa Barbara, says 22-year-old student Ryan Roberts, "everybody does them." The long-term health risks of this experimentation are not yet known, but doctors are worried about higher cancer risk

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