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Estimated Glomerular Filtration Rate (eGFR) and Disease Stage 48 In stage 1 , the eGFR is within normal limits (90 mL/min/1.73 m 2 ) and the kidneys are still working adequately, but the presence of protein in the urine is indicative of mild kidney damage

In this context, analytical methods such as HPLC peptide analysis and LC-MS verification can help evaluate purity, identity, molecular characteristics, and research material consistency

Depending on its exact composition (and origin), propolis may also exhibit powerful local antibiotic and antifungal properties [58,59,60,61]

CYP24A1, a gene that provides instructions for making the enzyme 24-hydroxylase, is involved in the catabolism of both 25(OH)VD 3 and 1,25(OH) 2 D 3, thereby limiting vitamin D receptor (VDR)/1,25(OH) 2 D 3 signaling 14