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Histological findings further show thrombosis in terminal pulmonary arterioles and capillaries, as well as hyaline membranes lining the walls of alveoli, indicating high protein exudate from extensive capillary injury

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In 1978, building on this discovery, Zamecnik and Stephenson 32 used specific oligodeoxynucleotide chains that target the 35S RNA of the Rous sarcoma virus to inhibit virus replication, marking a prototype for the application of antisense oligonucleotide (ASO) drugs in disease treatment

But at night, it can be hard to tell a fox from a cat