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L-Carnitine L-Carnitine is an amino acid derivative that shuttles fatty acids into the mitochondria, the energy-producing centers of your cells

In people who also had type 2 diabetes historically a harder population to move SURMOUNT-2 still produced 12.8% and 14.7% reductions (PMID 37385275)

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Consistent with these findings, in vivo experiments revealed a significant reduction in Sirt1 protein expression in the livers of mice upon NNMT knockdown