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4704-C GENOMIC CHARACTERISTICS OF HEPATOCELLULAR CARCINOMA PATIENTS WITH RESPONSE TO SORAFENIB Yim Sun Young 1 , Ji Hoon Kim 1 , Hyung Joon Yim 2 , Yeon Seok Seo 1 , Jong Eun Yeon 1 , Young-Sun Lee 1 , Taehyung Kim 3 , Seong Hee Kang 4 , Yoonseok Lee 1 , Jong Su Kim 1 , Chang Hee Jung 1 and Korea University Hospital, (1)Korea University Hospital, (2)Korea University Ansan Hospital, Ansan, Republic of Korea, (3)Korea University Ansan Hospital, (4)4 Seasons Granwell Corp

At the optimized cut-off value of 11.1 kPa for cirrhosis diagnosis, TE showed 81% sensitivity, 81% specificity, PPV of 68.5% and a NPV of 89%

Using a probability level of 0.06 which was selected for high sensitivity, the FFI had a sensitivity of 91.6%, a specificity of 38.4%, PPV of 12.7% and NPV of 97.9%

Mendelian Randomization (MR) serves as an epidemiological approach for investigating causal links between exposure factors and outcome variables