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Protease-mediated maturation of HIV: inhibitors of protease and the maturation process

(20) conducted a study on mice, revealing that oxidative stress damage in aged oocytes results in diminished expression of protein phosphatase 2A (PP2A) at the centromere, reduced dephosphorylation of the Rec8 protein, compromised protection mechanisms of adhesion proteins within the oocyte, inhibition of oocyte division and maturation, and the emergence of aneuploidy

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