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Further research on the various HGF/c-Met physiological and pathological activities, as well as the elucidation of the pathways mediating them, will contribute to the development of more promising HGF/c-Met axis-based molecules with therapeutic effects

FOXO4-DRI prompted relocation of p53-pS15 and FOXO4 in the serum limitation-induced senescent fibroblast model Double immunofluorescence staining was performed to investigate the distribution of p53-pS15 and FOXO4 in serum limitation-induced senescent fibroblasts model with or without treatment with FOXO4-DRI (Fig