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However, if there is no substantial clinical improvement by day 5, treatment may be extended to 10 days

The hypothesis that GSSG functions as the oxidant for class III peroxidases during ROS production in apoplast, however, is not consistent with previous observations that a GSH peak was not observed in a bean apoplastic fluid before and after an oxidative burst and glutathione was less effective for the production of reactive oxygen species than free cysteine in an in vitro assay 37,38

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