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Abstract Background: Chronic obstructive pulmonary disease (COPD) is a common respiratory disorder manifested as chronic airway inflammation and persistent airflow limitation with the essential mechanism as inflammatory response and oxidative stress induced by toxic exposures such as cigarette smoke (CS)

Alpha-synuclein, for example, contributes to the aggregation of beta-amyloid and tau compounds, tau compounds contribute to the aggregation of alpha-synuclein (Pan et al., 2021), and Lewy bodies have been observed not just in Parkinsons but in other neurodegenerative disease as well (Wong and Krainc, 2017)

Causes of symptoms and symptom persistence in long COVID and myalgic encephalomyelitis/chronic fatigue syndrome

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