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Therefore, it is reasonable to speculate that ammonia-induced cell death may not be a form of cell death unique to CD8 + T cells

10.1002/fsn3.2762 202

Mutations in superoxide dismutase 1 ( SOD1 ), C9orf72 (chromosome 9 open reading frame 72), and TARDBP (TAR DNA-binding protein 43) are associated with familial ALS, whereas the majority of ALS cases are sporadic [100, 101]

177 HSP27 also facilitates STAT3 phosphorylation, either through IL-6 signaling or independently, leading to STAT3 nuclear translocation and its binding to the TWIST promoter