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It has also been suggested that RSV CP forms a groove structure required for RNA binding that is dependent on the amino acids Arg 77 , Thr 79 , Asp 80 , Lys 87 , and Arg 122

129 While the primary endpoints were not met, an unexpected finding emerged four weeks after treatment cessation: patients receiving 50 mg/day of nivalexanil exhibited significantly higher THI scores than placebo recipients, raising concerns about possible rebound effects or symptom exacerbation after withdrawal

In addition, equol improves IVM in porcine oocytes by activating the Nrf2/KEAP1 antioxidant pathway, decreasing ROS levels, and increasing the expression of haem oxygenase (HO-1), catalase(CAT), glutathione peroxidase 1 (GPX1) and SOD, and attenuating OS [111]