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If the patients concern involves growth hormone or IGF-1 signaling, body composition, or another endocrine issue, the evaluation is different again

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If a patient has a particularly high-risk thrombophilia (for example, antiphospholipid syndrome with prior arterial clots, or recurrent unprovoked VTE), a discussion with their physician is needed to decide if fasting is safe or if temporary prophylactic measures are warranted

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