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Systemic Inflammatory Response Shock-like Reaction A recent (2025) case report described a patient who developed full-blown systemic inflammatory response syndrome (SIRS) after a high-dose, unregulated glutathione infusion for cosmetic skin-lightening

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Mechanistic insights into folic acid-dependent vascular protection: dihydrofolate reductase (DHFR)-mediated reduction in oxidant stress in endothelial cells and angiotensin II-infused mice: a novel HPLC-based fluorescent assay for DHFR activity