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Specifically, the proportion of Fusobacteriota and Proteobacteria was markedly higher in the AC group of APP/PS1 model mice compared to the NC group of wild-type mice, indicating that AD pathology may be associated with the expansion of these potentially harmful phyla

33 , 17011715.e5 (2021)

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It has been demonstrated to induce mitochondrial damage and both intrinsic apoptotic and mPTP-driven cell death 13,14,15,16 via signalling pathways, indicating that its mode of action may involve BAX and BAK1