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It may be that Bacopa works better for some individuals than others, possibly depending on their specific symptom profile or if they have comorbid anxiety (since Bacopa also reduces anxiety)

73 The activity of GPx is also reduced in diabetes due to a decrease in the availability of its cofactor, selenium

These abnormalities persist in some patients despite the normalization of thyroid hormone levels, again pointing to the limitations of conventional therapy in fully reversing neural instability

However, a confirmatory test may be necessary when the combination of your symptoms points to a different medical problem