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Combined, these results suggest that glutathione is an important host resistance mechanism, but that also and ability to withstand host ROS, and potentially use this as a trigger for zoospore production, is important for Bd virulence

While its direct free radical scavenging activity is modest compared to classical antioxidants, creatine nonetheless contributes to redox homeostasis by reducing reactive oxygen species (ROS) and preserving mitochondrial integrity

Washington, DC: National Academy Press, ISBN 0-309-06997-1 Minson, D.J

Recent research shows it alleviates inflammation in conditions like silicosis and ulcerative colitis by targeting pathways like SIRT1/STAT3, promoting tissue repair and reducing oxidative stress without systemic toxicity (10)