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Glutathione is important when it comes to the transportation of amino acids through cell membranes, and it is also a necessary component for some enzymatic reactions to take place such as catalysis, signal transduction, metabolism, apoptosis and gene expression

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Therefore, 6-month-old male mice were utilized for establishing MIA-induced OA model in this study, and their skeletal system is fully matured, considered comparable to that of a 30-year-old human 37