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The commonly used reporter 10xStat92E-GFP (Bach et al, 2007) is composed of five copies of Socs36E intron 1 enhancer element, each of which contains at least two Stat92E-binding sites, and these are fused to a hsp70 minimal promoter and EGFP to detect enhancer activity

Sebaceous and sweat gland function decreases, leading to drier, less hydrated skin, and loss of elastic fibers impairs skin pliability (Zouboulis and Boschnakow, 2001

10.1111/gcb.13041 154 SollidJ.NilssonG

Elevated prostaglandins and wider inflammatory signals, including C-reactive protein, track with severity and are implicated in long-term health risks