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Deficiency is also high in those who have had intestinal surgery including weight loss surgeries such as gastric sleeves/bands

Tbx1 haploinsufficiency has no significant effect on the brain transcriptome We next sought to identify the transcriptional changes associated with the metabolic alterations identified in Tbx1 +/ mice

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Combined with the proliferation finding, it suggests the peptide may support DPC populations by both adding new cells and keeping existing ones alive longer