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A Multi-Center, Open-Label, Phase I Study of Single Agent RG7112: A First in Class p53-MDM2 Antagonist, in Patients with Relapsed/Refractory Acute Myeloid and Lymphoid Leukemias (AML/ALL) and Refractory Chronic Lymphocitic Leukemia/Small Cell Lymphocytic Lymphomas (CLL/SCLL)

MTX and Epal was oral administrated, NAC was intraperitoneal injection

Eight of these criteria include a history and physical examination which includes cheek rash, disc-like rashes, photosensitivity, oral ulcers, arthritis, inflammation of lung or heart membranes, kidney involvement, and nerve involvement with seizures or psychosis

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