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M.HammettA

The design and discovery of lixisenatide for the treatment of type 2 diabetes mellitus

BNIP3 is a member of the BH3-only subfamily whose expression is promoted by HIF-1 transcriptional activity

Interestingly, ITE, another AhR ligand, inhibits TGF-1induced myofibroblast differentiation through an AhR-independent mechanism by blocking Smad2/3/4 nuclear translocation [116]