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not peer-reviewed) Rossino G, Marchese E, Galli G, et al

TMEM9 downregulates APC expression and disrupts the protein destruction complex though v-ATPase-induced lysosomal protein degradation, which prevents -catenin degradation

Conclusion: Our study findings provide a comprehensive metabolomic knowledge base and other soluble biomarkers for a better understanding of the pathophysiology of LC and suggests sarcosine and serine supplementations might have potential therapeutic implications in LC patients