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Biomarkers of oxidative damage including malondialdehyde, F2-isoprostane, protein carbonyls and advanced glycation end products (AGE) are reported to be elevated in either the plasma, erythrocytes or liver of streptozotocin (STZ)-induced diabetic rats [228231], as well as in the plasma or urine of diabetic patients [232234], giving further evidence of ROS contribution to the onset, progression and pathological consequence of diabetes

What's the difference between treating B12 deficiency with injections versus tablets

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Over time, you can start to feel increasingly tired, anxious, and unable to get rest