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Drugging the NLRP3 inflammasome: from signaling mechanisms to therapeutic targets

ICAM-1 on the luminal surface of endothelial cells is induced to a greater extent in mouse retina than in other tissues in diabetes

Therefore, the ferroptosis pathway shows great potential as a target in the treatment of drug-resistant tumors, ischemic organ injury and neurodegenerative diseases, and inducing or inhibiting ferroptosis has become a new strategy to treat human diseases

Lipotropic injections typically contain methionine, inositol, choline, and L-carnitine, but lack high-quality randomised controlled trial evidence for weight loss