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Bertolini A, Ferrari A, Ottani A, Guerzoni S, Tacchi R, Leone S (2006)

Free radicals, reactive oxygen species, oxidative stress, oxidation, antioxidants

However, the protective effect of nicotinamide mononucleotide is significantly compromised if GPX4 expression is inhibited, indicating that the protective mechanism of nicotinamide mononucleotide largely relies on the normal function of GPX4

The forward and reverse oligonucleotides of the sequence 5-GAA A GA A GC C AC G TC A GT T -3, carrying silent third-codon base point mutations (mutant nucleotides underlined) were used for mito GCLmut