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Description

Blood (2017) 130:121

Appl Biochem Biotechnol 166:402413

11 IL-33 plays a role in in promoting type II immunity and functions to maintain alveolar macrophages with a M2 phenotype that reduce pro-inflammatory responses, although they do not impact on postnatal alveolarization

These goals cannot always be met by the format of a single vector DNA vaccine, particularly wherein competing goals are embodied within one DNA sequence