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Commercially available crotonic acid was used as a standard in parallel with a conversion ratio of 0.893 (Koch et al., Non-targeted Metabolome Profiling Analysis by Gas Chromatography-Mass Spectrometry (GC-MS) The metabolome profiling of the metabolite fraction enriched with primary metabolites was performed as previously described (Kopka et al., 750 = 0.71.0 cultures were extracted for 15 min at 37C by 1 ml methanol:chloroform:diethylamine 2.5:1.0:1.0 (v/v/v)

Singlet oxygen is the major reactive oxygen species involved in photooxidative damage to plants

1 Introduction Periodontitis is a globally prevalent chronic inflammatory disease triggered by dysregulation of oral biofilm and host immune responses, serving as the primary cause of adult tooth loss (1)

GLP-1-directed delivery of the NMDA receptor antagonist MK-801 affects neuroplasticity in the hypothalamus and brainstem