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Moreover, ASO 56 treatment reduced blood alanine aminotransferase (ALT) levels and attenuated PSC-induced liver fibrosis, characterized by 'onion skin' fibrosis, and detected by Sirius red staining

In addition, MPO generated by neutrophils during inflammation may result in irreversible protein and lipid alterations and increased levels of oxidized low-density lipoprotein, thereby promoting atherogenesis [87]