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Despite this promise, several critical limitations remain: No large-scale, randomized controlled human trials to confirm efficacy, safety, or long-term impact Toxicology and pharmacokinetic data are lacking, especially for chronic use or high-dose regimens Only one stereoisomer (all-L form) has been tested

1999;39(suppl 2):S20-S26

Additionally, if you are analyzing plasma amino acids on your patients, the glutamate/(serine + glycine) index developed by Gaggini et al could be a sensitive indicator identifying risk in FLD