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Description

Our findings demonstrate that glyphosate triggers renal damage via three interconnected pathways: (1) suppression of antioxidant defense systems and induction of oxidative stress, (2) activation of TLR-4-mediated inflammatory cascades, and (3) disruption of mitochondrial integrity leading to apoptotic cell death

[PubMed: 11015467] 376

Singh C, Shekhar A, Singh R

The results from this study could help guide future in vivo toxicity research of glyphosate and Roundup products, and further improve the policy to protect the environment and human health against herbicide use