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The authors acknowledge the support of the Open Access Publication Fund of the University of Duisburg-Essen

Metabolites derived from dietary components and microbial fermentation, as well as signaling pathways like the aryl hydrocarbon receptor (AHR) pathway, contribute to the induction of iTreg cells in the intestine (141, 148, 149)

The experimental design consisted of six groups, each comprising 10 animals (n = 10)

We showed that norepinephrine (NE, 50 M) or dopamine (DA, 50 M) exerted potent protective effect against glutamate-induced cytotoxicity, but this effect was not observed when other neurotransmitters such as histamine, -aminobutyric acid, serotonin, glycine and acetylcholine were tested