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5.1 Interventions validated in cellular models Several therapies have demonstrated proof-of-concept in vitro using glial and neuronal cells

Twenty-six of the reactions were recorded 5 minutes post-dose

If you must store reconstituted solution for a brief period of time: Keep the vial in the refrigerator at the temperatures indicated Protect the vial from all light in an amber vial, and for no longer than the timeframe specified by your compounding pharmacy (typically 24 hours maximum) Do not freeze reconstituted solution, as freeze-thaw cycles destroy potency while introducing aggregation risk Route-Specific Glutathione Considerations Intravenous IV-administered GSH increases plasma glutathione transiently, but please know extracellular GSH is rapidly degraded by the enzyme gamma-glutamyltransferase (GGT) (this limits reliable elevation of intracellular GSH levels)

More recently, the thiol donors glutathione, cysteine, and taurine, have generated interest for the improvement of exercise recovery and performance, with their potential to boost endogenous antioxidant defence in a way that generalized antioxidants cannot