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Some eligible studies have demonstrated the action of caffeine on glial cells through changes in GFAP and Iba-1 expression in stress-specific brain areas [27, 29]

*Correspondence: Yue Deng, [email protected]

Journal of Cellular Physiology 207 (2), 331339

To support these functions, the cell maintains NAD in a largely oxidized state (NAD + ) to serve as oxidizing agent for catabolic reactions, while NADP is kept largely in a reduced state (NADPH) to readily donate electrons for reductive cellular processes (4, 6)