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Jump Back to Main Peptides List TB-500 The basics: TB-500 is a synthetic peptide designed to mimic a small fragment of TB-4 (thymosin beta-4), a naturally occurring protein found throughout your body thats involved in tissue repair, inflammation reduction, and cell movement

Mechanistically, inhibition of PDGFR ablates FGF-2-recruited perivascular coverage, exposing anti-VEGF agents to inhibit vascular sprouting

Myeloperoxidase - a bridge linking inflammation and oxidative stress with cardiovascular disease

Similar to rapamycin 31 , these effects were achieved even though not initiated until later in life, which we reasoned to be a safer therapeutic window for IGF-1R modulation than younger ages 34