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For quantification of melanolipofuscin and auto/phagolysosome granules (MLaPL), we opened each micrograph in Fiji/ImageJ Software and counted all aggregates of fused organelles such as melanolipufuscin, auto/phagolysosomes in RPE cells of 3 Lipe / and 3 Lipe +/+ mice ( n = 2026 TEM fields per group)

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If your body has been under significant oxidative stress, the initial "cleanup" might feel like a slight clearing of mental fog