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Rats became symptomatic with proteinuria approximately 6 weeks after irradiation and uremic morbidity occurred after 26 weeks

They found that the ferroptosis of murine fibrosarcoma MCA205 cells could increase the number of BMDCs with mature phenotype and exert a vaccine-like action in vivo, which suggested that ferroptosis could trigger an innate and adaptive immune response

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A total of 100 nM ABHD11-Flag was added to 100 M of the substrates (OGDHc-E2 peptides or succinyl-CoA) in assay buffer (50 mM TrisHCl pH 7.4, 100 mM NaCl) in 1.5 ml Eppendorf tubes for each condition on ice