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The results substantiated that luteolin bilosomes represent a safe, non-invasive, and efficacious approach, providing superior cognitive enhancements compared to traditional luteolin suspension (47)

The current cutoff values of TE are designed to assess liver fibrosis in patients with a singular liver disease, such as chronic hepatitis B (CHB) or non-alcoholic fatty liver disease (NAFLD)

In a recent phase 2a study, 40% (16/40) of patients with chronic hepatitis B treated with nine 4-weekly doses of HBV-targeted siRNA elebsiran (BRII835) in combination with the therapeutic vaccine BRII-179 developed robust anti-HBs antibodies, whereas none of the patients in the siRNA-alone arm showed the presence of antiHBs antibodies despite a 1.2-2.6-fold log reduction in serum HBsAg levels[75]