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This has been shown in several studies, including the one published in the Journal of Neuroendocrinology

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Intranasally administered labeled siRNA distributed along the olfactory pathway to the brain and was detected within the olfactory epithelium, the olfactory nerve as well as in the glomerular and mitral cell layer of the olfactory bulb [31]

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Palm U, Segmiller FM, Epple AN, et al

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