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Moreover, IHC staining with the serial sections from 15 human GB specimens revealed an inverse correlation between AATF expression and -H2AX levels (Fig

Consistent with this, KEGG pathway analysis revealed downregulation of -oxidation in KO mice, accompanied by upregulation of glycolysis and mitochondrial oxidative phosphorylation, reflecting a systemic shift in fuel preference toward carbohydrates driven by carnitine depletion and impaired fatty acid oxidation

S., Dewhurst, S

Summary Keywords bromelain, cancer, chemotherapeutics, cytotoxicity, apoptosis, molecular targets Citation Pezzani R, Jimnez-Garcia M, Cap X, Snmez Grer E, Sharopov F, Rachel TYL, Ntieche Woutouoba D, Rescigno A, Peddio S, Zucca P, Tsouh Fokou PV, Martorell M, Gulsunoglu-Konuskan Z, Ydyrys A, Bekzat T, Gulmira T, Hano C, Sharifi-Rad J and Calina D (2023) Anticancer properties of bromelain: State-of-the-art and recent trends