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SKU: 35837772899
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Description

10.1172/JCI174015 21 DubinR

Called tyrosine kinase inhibitors (TKIs), these agents bind to HER2 receptors on the cancer cell surface, thereby blocking the receptor signals that tell breast cancer cells to keep growing: Lapatinib (Tykerb ) received FDA approval in 2007 for HER2-positive breast cancer treatment in patients already treated with capecitabine (chemotherapy)